Figure 2

Single cancer view. The genome visualization provides a high level (macro) view to show similarities and differences across samples within a single cancer (Ovarian Cancer). This visualization is based around Circos [33], and allows for the display of high level aggregated features as concentric circles, with connecting arches showing identified associations, in this case common translocations. The concentric rings show, in this instance, information about the genes and karyotypes, and can include experiment information (e.g. identified mutations, methylation, expression). The associations are calculated, and in this instance show genes that have similar levels of disruptions. Selection of information allows for drill down into the related data sets, and filters can be applied which allow for control over the amount of information displayed.