Figure 4

mspecLINE Tool. The mspecLINE tool [46] enables the mining of associations between literature information regarding specific diseases and observed peptide spectra. The resulting peptide lists can then be used to generate transition lists for new experiments. The user starts exploration from a specific disease and then all proteins associated with that disease are then discovered. Associations are discovered using an information theory based measure called Normalized Medline Distance. The evidence for the associations, and identified proteotypic peptides can then be retrieved or displayed in Cytoscape.