Performance of strategies with different information sources on SABmark. Boxplots show developer (FD) score (equivalent to sum-of-pairs [SP] score) achieved by different alignment strategies for (A) "Twilight Zone" and (B) "Superfamily" sets in the SABmark benchmark database. Boxplots display first, second and third quartiles as vertical lines; outliers are shown as pluses. The strategies tested differ in the combination of pairwise sequence information that is used to construct the alignment graph. Combinations include: C, longest common subsequence, L, the four top scoring local alignments, G, global alignment, M, GTG motifs.