Figure 3From: Accelerated maximum likelihood parameter estimation for stochastic biochemical systemsPure-birth process MCEM2MLEs and confidence intervals. Colored circles depict MCEM2 MLEs normalized by true parameter values for the pure-birth model with θ ̂ ( 0 ) =1 and varying θ∗. Error bars denote 95% confidence intervals (CIs) for each model. Out of 100 models tested, only eight (centered at blue circles) do not overlap the true parameter values (green line) whereas the remaining 92 (centered at red circles) enclose the truth. This agrees well with the expected 95/100.Back to article page