Table 1 30 top-ranked KEGG pathways using a prior probability of 0.05
From: A Bayesian variable selection procedure to rank overlapping gene sets
KEGG pathway | Number of genes | Posterior probability of being included in the model | Odds ratio | Variance per gene (10^-3) |
|---|---|---|---|---|
ABC transporters | 24 | 1 | Infinity | 4.24 |
Lysosome | 90 | 1 | Infinity | 3.56 |
Proteasome | 40 | 1 | Infinity | 3.53 |
Complement and coagulation cascades | 53 | 1 | Infinity | 3.13 |
RIG-I-like receptor signaling pathway | 44 | 1 | Infinity | 2.80 |
ECM-receptor interaction | 63 | 1 | Infinity | 2.59 |
Cell adhesion molecules (CAMs) | 95 | 1 | Infinity | 2.50 |
Axon guidance | 79 | 1 | Infinity | 2.46 |
SNARE interactions in vesicular transport | 31 | 1 | Infinity | 2.39 |
RNA degradation | 49 | 1 | Infinity | 2.39 |
Ubiquitin mediated proteolysis | 105 | 1 | Infinity | 2.34 |
Neuroactive ligand-receptor interaction | 125 | 1 | Infinity | 2.27 |
PPAR signaling pathway | 58 | 1 | Infinity | 2.16 |
Ribosome | 76 | 1 | Infinity | 2.15 |
MAPK signaling pathway | 179 | 1 | Infinity | 2.11 |
Aminoacyl-tRNA biosynthesis | 34 | 1 | Infinity | 2.08 |
Endocytosis | 139 | 1 | Infinity | 2.08 |
Fc gamma R-mediated phagocytosis | 70 | 1 | Infinity | 2.00 |
Insulin signaling pathway | 97 | 1 | Infinity | 1.88 |
Cell cycle | 96 | 1 | Infinity | 1.85 |
Notch signaling pathway | 31 | 1 | Infinity | 1.73 |
Cytokine-cytokine receptor interaction | 115 | 1 | Infinity | 1.69 |
Chemokine signaling pathway | 138 | 1 | Infinity | 1.58 |
Metabolic pathways | 793 | 1 | Infinity | 1.47 |
Tight junction | 97 | 0.938 | 288 | 1.11 |
Purine metabolism | 117 | 0.927 | 240 | 1.16 |
Chronic myeloid leukemia | 58 | 0.919 | 215 | 1.27 |
Pathways in cancer | 227 | 0.847 | 105 | 0.945 |
Basal transcription factors | 23 | 0.826 | 90.3 | 1.28 |
Circadian rhythm - mammal | 5 | 0.590 | 27.4 | 1.77 |