From: Inferring high-confidence human protein-protein interactions
 | Proteini |  |  | Proteinj |  | Protein-protein interactioni-j | |||
---|---|---|---|---|---|---|---|---|---|
Symbol | Occurrence | Name | Symbol | Occurrence | Name | Occurrence O ij | Z-score | Z-rank | Average rank |
MDM2 | 466 | Mouse double minute 2 homolog | TP53 | 1097 | Tumor protein p53 | 130 | 86.0 | 3355 | 2999.8 |
TP53 | 1097 | Tumor protein p53 | UBC | 1899 | Ubiquitin C | 64 | 18.4 | 30486 | 16565.3 |
HBA2 | 68 | Hemoglobin, alpha 2 | HBB | 76 | Hemoglobin, beta | 59 | 395.5 | 76 | 1360.3 |
CBL | 414 | Cas-Br-M ecotro- pic sequence | EGFR | 626 | Epidermal growth factor receptor | 46 | 42.6 | 11054 | 6849.3 |
CBL | 414 | Cas-Br-M ecotro- pic sequence | GRB2 | 916 | Growth factor receptor bound 2 | 44 | 33.2 | 15615 | 9129.8 |
FANCA | 217 | Fanconi anemia, complementation A | FANCG | 143 | Fanconi anemia, complementation G | 43 | 117.3 | 1808 | 2226.3 |
EGFR | 626 | Epidermal growth factor receptor | UBC | 1899 | Ubiquitin C | 41 | 15.8 | 34796 | 18720.3 |
BRCA2 | 199 | Breast cancer 2, early onset | RAD51 | 171 | DNA repair protein RAD51 homolog 1 | 40 | 104.4 | 2288 | 2466.3 |
HIF1A | 207 | Hypoxia inducible factor 1, alpha | VHL | 351 | von Hippel-Lindau tumor suppressor | 39 | 69.2 | 5071 | 3857.8 |
HRAS | 164 | Ha-Ras1 proto-oncoprotein | RAF1 | 281 | Proto-oncogene c-RAF | 38 | 84.8 | 3444 | 3044.3 |
SNAP25 | 131 | Synaptosomal-associated protein, 25kDa | STX1A | 183 | Syntaxin 1A | 37 | 114.7 | 1920 | 2282.3 |
MAX | 145 | MYC associated factor X | MYC | 382 | Proto-oncogene c-Myc | 36 | 73.4 | 4568 | 3606.3 |
BARD1 | 109 | BRCA1 assoc. RING domain 1 | BRCA1 | 448 | Breast cancer 1, early onset | 35 | 75.9 | 4279 | 3461.8 |
GRB2 | 916 | Growth factor receptor bound 2 | SHC1 | 317 | SHC transforming protein 1 | 35 | 30.1 | 17593 | 10118.8 |
CDH1 | 167 | Cadherin 1, type 1 | CTNNB1 | 470 | Catenin, beta 1 | 34 | 57.8 | 6876 | 4760.3 |
E2F1 | 168 | E2F transcription factor 1 | RB1 | 385 | Retinoblastoma 1 | 34 | 64.0 | 5853 | 4248.8 |
GRB2 | 916 | Growth factor receptor bound 2 | SOS1 | 125 | Son of sevenless homolog 1 | 32 | 44.9 | 10232 | 6438.3 |
CCNA2 | 109 | Cyclin A2 | CDK2 | 286 | Cyclin-dependent kinase 2 | 31 | 84.3 | 3485 | 3064.8 |
EGF | 76 | Epidermal growth factor | EGFR | 626 | Epidermal growth factor receptor | 31 | 68.2 | 5211 | 3927.8 |
NFKBIA | 231 | Nucl. factor of kappa light chain gene enhancer in B-cells | RELA | 314 | V-rel reticulo-endotheliosis viral oncogene homolog A | 30 | 53.1 | 7932 | 5288.3 |