Step 1 |
For all genes, calculate their midpoints (average of start and end base pair position). Do the same for the features on DNA copy number array. |
Step 2 |
For each gene, calculate the distance between its midpoint and that of the DNA copy number array features (mapping to the same chromosome as the gene). See Figure 2. |
Step 3 |
Assign to each gene the DNA copy number data of the feature with minimum distance between its midpoint and that of the gene. |