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Table 1 Program attributes and characteristics

From: A comparative evaluation of sequence classification programs

Similarity-based Methods

Program

Similarity Method

LCA

Specific Genes Req’d

Interface

CARMA

BLAST, HMM

   

command line, web-based

FACS

other

   

command line

jMOTU/Taxonerator

BLAST, other

  

multiple alignment

command line

MARTA

BLAST

LCA-like

 

command line

MEGAN

BLAST

LCA-like

 

GUI

MetaPhyler

BLAST

  

marker genes

command line

MG-RAST

BLAST

  

marker genes

web-based

MTR

BLAST

LCA-like

 

command line

SOrt-ITEMS

BLAST

LCA-like

 

command line

Composition-based Methods

  

Program

Composition Method

Machine Learning

Confidence Method

Specific Genes Req’d

Interface

Naive Bayes Classifier

NBC

supervised

other

 

command line, web-based

PhyloPythiaS

other

supervised

  

command line, web-based

PhymmBL

IMM

supervised

other

 

command line

RAIphy

other

semi-supervised

  

GUI

RDP

k-means/kNN, NBC

supervised

bootstrap

16S rRNA

command line, web-based

Scimm

IMM

semi-supervised

  

command line

TACOA

k-means/kNN

supervised

  

command line

Phylogeny-based Methods

  

Program

Phylogeny Method

Confidence Method

Specific Genes Req’d

Interface

EPA

ML

bootstrap, other

multiple alignment

command line, web-based

FastTree

other

bootstrap

multiple alignment

command line

green genes (NAST, Simrank)

other

  

16S rRNA

web-based

pplacer

ML, Bayesian

posterior probability, other

multiple alignment

command line

Combined Similarity and Composition-based Methods

  

Program

Similarity Method

Composition Method

Machine Learning

Specific Genes Req’d

Interface

SPHINX

BLAST

k-means/kNN

supervised

 

web-based

Combined Similarity and Phylogeny-based Methods

  

Program

Similarity Method

Phylogeny Method

Confidence Method

Specific Genes Req’d

Interface

AMPHORA

HMM

other

bootstrap

marker genes

command line

MLTreeMap

BLAST, HMM

ML

bootstrap, other

marker genes

command line, web-based

SAP

BLAST

Bayesian, other

posterior probability, other

 

command line

Treephyler

HMM

other

bootstrap

marker genes

command line