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Table 6 MeSH-based bridges for the JIA domain

From: Exploring and linking biomedical resources through multidimensional semantic spaces

Disease

ProteinGene

Score

S

systemic rheumatoid arthritis

rheumatoid factor

coh = 0.290

105

systemic rheumatoid arthritis

IgG

coh = 0.262

95

essential anemia

ferritins

coh = 0.150

3

essential anemia

hemoglobins

coh = 0.150

3

recurrent polyserositis

proteins cytoskeletal

coh = 1.000

3

hyperhomocysteinemias

l-homocysteine

coh = 1.000

2

spondylitis rheumatoid

leukocyte antigens human

coh = 0.219

49

stills disease adult-onset

receptors IL-6

coh = 0.158

3

system lupus erythematosus

autoimmune antibody

coh = 0.206

29

disorder amyloid

SAA protein

coh = 0.828

24

disorder amyloid

substance amyloid

coh = 0.667

14

third disease

vaccine rubella

coh = 0.500

2

iron-deficiency anemias

transferrin receptor

coh = 0.750

3

infection

interferon

coh = 0.286

2

thyromegaly

SAA protein

coh = 0.500

2

myasthenia gravis

acetylcholine receptor

coh = 1.000

2

hyperimmunoglobulinemias

IgD

coh = 0.375

3

uveitis

factors antinuclear

coh = 0.184

49

thyroid insufficiency

thyroxine

coh = 1.000

2

thyroid insufficiency

thyroglobulins

f1 = 0.500

2

rickets celiac

gliadin

coh = 0.800

4

castleman's disease

receptors IL-6

coh = 0.833

5

castleman's disease

IL-6

coh = 0.833

5

  1. Best δ-maximum scored bridges between the Disease and ProteinGene levels for the the JIA domain, using the gold-standard (MeSH). Interestingness measures used are: cohesion (coh), confidence (conf) and f-measure (f1). The column S indicates the number of documents supporting each bridge.