Skip to main content
Figure 5 | BMC Bioinformatics

Figure 5

From: Accuracy of RNA-Seq and its dependence on sequencing depth

Figure 5

False discovery rate (FDR) and receiver operating characteristic (ROC) for three data sets. (a) and (b) Caltech dataset; (c) and (d) Chiang dataset; (e) and (f) Bullard dataset. Three panels on the left indicate the FDR. FDR (on y-axis) is plotted against the number of most significantly differentially expressed genes (on x-axis). Three panels on the right indicate the ROC. Bi denotes binomial distribution; BB denotes beta-binomial distribution. The line for BB γ = 0 was obtained by setting γ = 0 and optimizing D i . It corresponds to the normal beta-binomial distribution. In (b), the line for BB γ = 0 overlap with the line for BB γ = 0.3.

Back to article page