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Table 3 Top search results of colorectal cancer advanced search

From: PAGED: a pathway and gene-set enrichment database to enable molecular phenotype discoveries

Gene-set Name

Hits

P value

FDR

Data Source

Molecular Mechanisms of Cancer

38

2.48E-17

7.04E-10

Protein Lounge

PI3K Signaling

33

2.01E-13

7.04E-10

Protein Lounge

Akt Signaling

27

9.6E-13

7.04E-10

Protein Lounge

ERK Signaling

24

1.53E-10

7.04E-10

Protein Lounge

GSK3 Signaling

23

1.32E-13

7.04E-10

Protein Lounge

inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages

9

3.7E-11

7.04E-10

BioCarta

atm signaling pathway

8

6.28E-11

7.04E-10

BioCarta

wnt signaling pathway

7

7.7E-09

7.04E-10

BioCarta

cell cycle: g2/m checkpoint

7

2.14E-08

7.04E-10

BioCarta

cell cycle: g1/s check point

7

2.14E-08

7.04E-10

BioCarta

Canonical Wnt signaling pathway

8

9.24E-10

7.04E-10

NCI-Nature

Presenilin action in Notch and Wnt signaling

8

3.16E-08

7.04E-10

NCI-Nature

Plasma membrane estrogen receptor signaling

7

1.41E-08

7.04E-10

NCI-Nature

FOXM1 transcription factor network

7

2.48E-07

7.04E-10

NCI-Nature

LPA receptor mediated events

7

1.45E-06

7.04E-10

NCI-Nature

Metabolism of xenobiotics by cytochrome P450

20

3.3E-25

7.04E-10

KEGG

Drug metabolism - cytochrome P450

17

4.96E-21

7.04E-10

KEGG

Bladder cancer

15

3.29E-18

7.04E-10

KEGG

Cytokine-cytokine receptor interaction

15

1.39E-06

7.04E-10

KEGG

Colorectal cancer

14

4.43E-14

7.04E-10

KEGG

p53 signaling pathway

14

4.92E-14

7.04E-10

KEGG

Prostate cancer

14

1.66E-12

7.04E-10

KEGG

Xenobiotics

5

3.32E-08

7.04E-10

Reactome

Formation of incision complex in GG-NER

5

5.75E-06

7.04E-10

Reactome

Global Genomic NER (GG-NER)

5

5.75E-06

7.04E-10

Reactome

Dual incision reaction in GG-NER

5

5.75E-06

7.04E-10

Reactome

Exocytosis of Alpha granule

5

0.000217

1.95E-08

Reactome

SIGNAL_TRANSDUCTION

55

8.36E-28

7.04E-10

MsigDB

BIOPOLYMER_METABOLIC_PROCESS

49

4.16E-22

7.04E-10

MsigDB

KEGG_PATHWAYS_IN_CANCER

43

9.9E-46

7.04E-10

MsigDB

NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS

41

2.16E-20

7.04E-10

MsigDB

NUCLEUS

41

1.8E-18

7.04E-10

MsigDB

Immune_Kong10_5640genes_ImmPort_ComprehensiveListofImmune-RelatedGenes

114

3.61E-49

7.04E-10

GeneSigDB

Lymphoma_Melendez05_4229genes

81

1.57E-39

7.04E-10

GeneSigDB

Breast_Farmer05_3198genes_basal_apocrine_luminal

66

1.08E-21

7.04E-10

GeneSigDB

Ovarian_Crijns09_2394Genes_17PathwayPredictor

57

7.94E-30

7.04E-10

GeneSigDB

StemCell_Nilsson07_3742genes

45

4.86E-07

7.04E-10

GeneSigDB

hsa-miR-19a

3

1.49E-05

8.43E-09

miRecords

[hsa-miR-21]

3

0.000116

8.43E-09

miRecords

hsa-miR-204

3

0.000164

1.95E-08

miRecords

hsa-miR-21

3

0.000953

2.72E-07

miRecords

hsa-miR-125b

3

0.003089

2.72E-07

miRecords