Table 5 Top 20 gene sets ranked by differential gene-set expressions in the CRC-specific gene-set association network (GSAN)
From: PAGED: a pathway and gene-set enrichment database to enable molecular phenotype discoveries
Gene-set name | Scale | Data Source | NORM_ABS_FC |
|---|---|---|---|
Colon_Kim04_235genes | 151 | GeneSigDB | 48.58225017 |
SABATES_COLORECTAL_ADENOMA_DN | 292 | MsigDB | 43.9233159 |
SIGNAL_TRANSDUCTION | 1598 | MsigDB | 32.5957784 |
Leukemia_Pellegrini08_2692genes | 2122 | GeneSigDB | 31.65148925 |
SABATES_COLORECTAL_ADENOMA_UP | 142 | MsigDB | 31.65000681 |
Breast_Parker09_1918genes_IntrinsicGenes _Compilation | 1734 | GeneSigDB | 20.85621131 |
Lymphoma_Melendez05_4229genes | 2570 | GeneSigDB | 19.38449282 |
Breast_Farmer05_3198genes_basal _apocrine _luminal | 3125 | GeneSigDB | 18.93820407 |
SMID_BREAST_CANCER_LUMINAL_B_DN | 648 | MsigDB | 18.13762096 |
Intestine_Vecchi07_1024genes | 796 | GeneSigDB | 16.68882931 |
Ovarian_Crijns09_2394Genes _17PathwayPredictor | 1586 | GeneSigDB | 15.29529767 |
hsa-miR-204 | 19 | miRecords | 14.37015815 |
StemCell_Nilsson07_3742genes | 3624 | GeneSigDB | 12.47045771 |
Immune_Kong10_5640genes_ImmPort _ComprehensiveListofImmune-RelatedGenes | 4549 | GeneSigDB | 11.91186233 |
cell cycle: g1/s check point | 53 | BioCarta | 9.84279867 |
Bladder cancer | 89 | KEGG | 7.885181064 |
Drug metabolism - cytochrome P450 | 94 | KEGG | 7.837851592 |
Metabolism of xenobiotics by cytochrome P450 | 103 | KEGG | 7.837805455 |
hsa-miR-21 | 34 | miRecords | 7.001844224 |
KEGG_PATHWAYS_IN_CANCER | 328 | MsigDB | 6.792625895 |