Figure 6
From: Computational approaches to protein inference in shotgun proteomics
An example of a Bayesian network used in the Fido model. Three layers mimic the LC-MS/MS experiment in which proteins are first digested into peptides which are then matched to the MS/MS spectra. The numbers associated with the directed edges correspond to PSM identification scores between the peptide and spectrum layers, while α, β, and γ are the three parameters used in Fido. Note that unidentified peptides are not modeled.