Figure 2
From: Statistical methods for quantitative mass spectrometry proteomic experiments with labeling
Box plots of global protein abundance distribution. Box plots for A) the yeast spike in study, B) the GCM study and C) the prostate cancer study. The log2 scale raw mass spectrometric signal abundance (labeled on the raw scale) is plotted as a function of MS experiment number. Sort order in A is first by MS experiment and then by tag, and boxes are grouped in sets of 8 where the first four (dark grey) are the first technical replicate MS experiment and the second four (light grey) are the second technical replicate MS experiment for a given spike-in combination. Sort order in B was chosen to be first by tag and then by MS experiment in order to help assess whether a systematic tag bias was present. Sort order in C is first by MS experiment and then by tag. (Panel B is reproduced with permission from [9]. Copyright 2008 American Chemical Society.)