Figure 1From: Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: a study of the HMG domainA) Structure alignments of 18 HMG box domains from various proteins bound to DNA (cyan). Amino acids in red were NVs conserved 90% or greater in the 69 HMG sequences. B) Alignments of 7 SOX specific HMG box structures with NV amino acids in purple conserved 90% or greater in the 20 human SOX sequences.Back to article page