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Figure 3 | BMC Bioinformatics

Figure 3

From: Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: a study of the HMG domain

Figure 3

A) NV at amino acid 16 (green) located on the back side of DNA binding on helix 1. MD simulations show increased movement of the NV (red) compared to the normal Sox9 (blue) at amino acid 16. B) NV at amino acid 45 (green) at the beginning of the third helix. An acidic amino acid leads to an increase in movement (red) over the normal alanine (blue).

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BMC Bioinformatics

ISSN: 1471-2105

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