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Table 1 Summary of THINK-Back tools and adjustment methods

From: THINK Back: KNowledge-based Interpretation of High Throughput data

THINK-Back Method

Abbr.

Adjustment to prior methods

 
  

GSEA[19]

GSA[24]

LRpath[23]

 

Gene Appearance Frequency

AF

GSEA-AF

-

LRpath-AF

 

Density Analysis

DS

GSEA-DS

GSA-DS

LRpath-DS

 
  1. Our two THINK-Back adjustment methods can be used in combination with previously-developed gene set enrichment tools.