Dataset | #Pways | GSA-DS | LRpath-DS | GSEA-DS |
---|
| | 0 - 10 |
> 10
| TOTAL | 0 - 10 |
> 10
| TOTAL | 0 - 10 |
> 10
| TOTAL |
---|
Breast GSE-2990 | 18 | 8 | 5 | 13 | 7 | 8 | 15 | 6 | 7 | 13 |
Breast GSE-3494 | 18 | 9 | 5 | 14 | 8 | 5 | 13 | 10 | 5 | 15 |
Lung Boston | 18 | 4 | 4 | 8 | 4 | 9 | 13 | 5 | 6 | 11 |
Lung Michigan | 18 | 6 | 7 | 13 | 4 | 6 | 10 | 7 | 7 | 14 |
AVERAGE
|
7
|
5
|
12
|
6
|
7
|
13
|
7
|
6
|
13
|
- This table presents the summary of improvement in rankings for 19 cancer-related KEGG signaling pathways, when using the DS-adjusted methods. We can observe that out of these 19 cancer-related pathways, DS-adjusted methods improve the rankings of more than half of the pathways, with LRpath-DS showing average improvements in the rankings of 78% of the mentioned signaling pathways. We also differentiate between large ranking improvements (greater than 10 ranks), and observe that GSEA-DS has an average rank improvement greater than ten ranks in 69% of the studied pathways.