Figure 1From: Interfacing medicinal chemistry with structural bioinformatics: implications for T box riboswitch RNA drug discoveryT box transcription antitermination mechanism. a) Uncharged, cognate tRNA binds the 5' -untranslated region of the nascent mRNA and stabilizes the antiterminator. b) In the absence of uncharged, cognate tRNA, the more stable terminator forms and transcription is terminated before the translation start site.Back to article page