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Table 2 High-degree CC and BP functional clusters in the H. sapiens summary (k = 400)

From: FUSE: a profit maximization approach for functional summarization of biological networks

CC functional cluster

Degree

BP functional cluster

Degree

Heterogeneous nuclear ribonucleoprotein complex

183

Actin filament bundle assembly

208

Cytosolic large ribosomal subunit

161

Regulation of defense response to virus by virus

206

Cytosolic small ribosomal subunit

158

Negative regulation of catabolic process

204

Coated pit

158

Peptidyl-threonine phosphorylation

200

Mitochondrial nucleoid

149

Signal complex assembly

189

Chaperonin-containing T-complex

148

Positive regulation of protein complex assembly

182

CRD-mediated mRNA stability complex

141

Regulation of nitric oxide biosynthetic process

181

NuA4 histone acetyltransferase complex

136

Glial cell development

178

Actin filament

135

Cell killing

178

Actomyosin

134

Regulation of cytokine-mediated signaling pathway

174

Clathrin coat of coated pit

133

Protein stabilization

174

Nonhomologous end joining complex

124

Actin filament capping

170

Endocytic vesicle membrane

124

Activation of MAPKK activity

169

Nucleosome

124

T cell receptor signaling pathway

164

Nuclear inner membrane

123

Regulation of RNA splicing

164