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Table 2 High-degree CC and BP functional clusters in the H. sapiens summary (k = 400)

From: FUSE: a profit maximization approach for functional summarization of biological networks

CC functional cluster Degree BP functional cluster Degree
Heterogeneous nuclear ribonucleoprotein complex 183 Actin filament bundle assembly 208
Cytosolic large ribosomal subunit 161 Regulation of defense response to virus by virus 206
Cytosolic small ribosomal subunit 158 Negative regulation of catabolic process 204
Coated pit 158 Peptidyl-threonine phosphorylation 200
Mitochondrial nucleoid 149 Signal complex assembly 189
Chaperonin-containing T-complex 148 Positive regulation of protein complex assembly 182
CRD-mediated mRNA stability complex 141 Regulation of nitric oxide biosynthetic process 181
NuA4 histone acetyltransferase complex 136 Glial cell development 178
Actin filament 135 Cell killing 178
Actomyosin 134 Regulation of cytokine-mediated signaling pathway 174
Clathrin coat of coated pit 133 Protein stabilization 174
Nonhomologous end joining complex 124 Actin filament capping 170
Endocytic vesicle membrane 124 Activation of MAPKK activity 169
Nucleosome 124 T cell receptor signaling pathway 164
Nuclear inner membrane 123 Regulation of RNA splicing 164