Figure 3From: Predicting folding pathways between RNA conformational structures guided by RNA stacksTwo different folding pathways that form an identical stack. Two different folding pathways that form an identical stack. Left: The stack is formed successively. Right: The stack is constructed by random formation of base pairs. The right pathway yields a higher energy barrier because the randomly introduced base pairs form unpaired loop regions that result in additional entropic penalties.Back to article page