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Table 1 Fraction of interactions in a pathway that occur in any significant most-perturbed sub-pathway

From: Sensitive detection of pathway perturbations in cancers

Pathway #cancers perturbed in #measured interactions #perturbed interactions %perturbed interactions
Alpha6 Beta4 Integrin 14 32 24 75
B Cell Receptor 13 105 79 75.2
EGFR1 16 78 45 57.7
ID 1 53 15 28.3
IL-2 17 75 53 70.7
IL-3 18 58 38 65.5
IL-4 11 36 25 69.4
IL-6 3 46 23 50
IL-7 4 20 12 60.0
Kit Receptor 12 55 29 52.7
T Cell Receptor 12 102 67 65.7
TGF-beta Receptor 15 155 87 56.1
TNF-alpha 17 109 82 75.2
  1. The third column contains the number of interactions that connect genes that are also present in the gene expression data.