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Table 1 Fraction of interactions in a pathway that occur in any significant most-perturbed sub-pathway

From: Sensitive detection of pathway perturbations in cancers

Pathway

#cancers perturbed in

#measured interactions

#perturbed interactions

%perturbed interactions

Alpha6 Beta4 Integrin

14

32

24

75

B Cell Receptor

13

105

79

75.2

EGFR1

16

78

45

57.7

ID

1

53

15

28.3

IL-2

17

75

53

70.7

IL-3

18

58

38

65.5

IL-4

11

36

25

69.4

IL-6

3

46

23

50

IL-7

4

20

12

60.0

Kit Receptor

12

55

29

52.7

T Cell Receptor

12

102

67

65.7

TGF-beta Receptor

15

155

87

56.1

TNF-alpha

17

109

82

75.2

  1. The third column contains the number of interactions that connect genes that are also present in the gene expression data.