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Table 2 Species and parameters included in the mathematical model.

From: Characterization of an inducible promoter in different DNA copy number conditions

Parameter or species Description Value Units
X LuxR protein concentration per cell Variable AU cell-1
A LuxR-HSL activated complex concentration per cell Variable AU cell-1
R RFP per cell Variable AU cell-1
H Inducer concentration Known input nM
n DNA copy number Estimated -
α tet LuxR synthesis rate per cell per DNA copy 2.3(a) AU min-1 cell-1
α lux Maximum RFP synthesis rate per cell per DNA copy Estimated AU min-1 cell-1
γ X LuxR protein degradation rate 6*10-2 min-1
μ Cell growth rate Estimated min-1
K H Dissociation constant of HSL-LuxR 553 nM
K A Dissociation constant of HSL-LuxR complex and luxI promoter Estimated AU cell-1
n H Hill cooperativity constant of HSL-LuxR 2 -
n A Hill cooperativity constant of HSL-LuxR complex and luxI promoter Estimated -
  1. (a)From unpublished data of our lab.
  2. Parameter values that have not been estimated in this study are described in [48]. AU indicates arbitrary units of RFP.