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Figure 3 | BMC Bioinformatics

Figure 3

From: Reconstructing cancer genomes from paired-end sequencing data

Figure 3

Reciprocal translocations in OV5. Examples of reciprocal Chr3/Chr7 (left) and Chr1/Chr3 (right) translocations in OV5. The Chr3/Chr7 translocation has the same multiplicity on the variant edges (red stars) as well as on the corresponding pairs of incident interval edges making it trivial. The Chr1/Chr3 translocation has different multiplicities on the variant edges (green stars) and is therefore non-trivial. In the Chr1/Chr3 translocation there is a single copy of Chr1 that does not use any variant edges, suggesting that only one copy of Chr1 is involved in the translocation, and that duplication of one of the translocated chromosomes occurs subsequent to the translocation.

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