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Table 2 Details of predicted protein interactions in M. tuberculosis

From: Inferring a protein interaction map of Mycobacterium tuberculosis based on sequences and interologs

Species Database Original PPI Predicted PPI Percentage (%)
By machine learning     
E. coli ECID 14,058(positive)+
27,882(negative)
12,899 27.97
By interolog     
Escherichia coli IntAct 14,158 16,468 35.71
Campylobacter jejuni IntAct 11,870 7,674 16.64
Treponema pallidum IntAct 3,744 324 0.70
Synechocystis IntAct 2,625 2,481 5.38
Myxococcus xanthus IntAct 384 253 0.55
Synechocystis sp. IntAct 219 220 0.48
Rickettsia sibirica IntAct 282 24 0.05
Streptococcus pneumoniae IntAct 193 47 0.10
Drosophila melanogaster DIP 22,650 1,558 3.38
Saccharomyces cerevisiae DIP 21,769 2,701 5.86
Caenorhabditis elegans DIP 3,979 229 0.50
Homo sapiens DIP 1,485 84 0.18
Mus musculus DIP 287 36 0.06
Rattus norvegicus DIP 69 2 0.15
Total: 46,119 interactions in 3,465 proteins (with 530 known PPIs)