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Table 5 Pre-processing methods

From: Comparison of data-merging methods with SVM attribute selection and classification in breast cancer gene expression

Preprocessing

Method

Background correction

Normalization

Summarization

RMA

Global correction from posterior mean given the observed PM

Quantile: intensities quantiles

Average

Linear model including array and probe effects fitting by median polish

Quantile -MBEI

-

Quantile: baseline intensities

Model assuming multiplicative probe effect and additive error

FrozenRMA

RMA-like

Quantile: reference distribution intensity

RMA-like including batch effect in the model