A systematic comparison of the MetaCyc and KEGG pathway databases

BMC Bioinformatics

Table 6 A comparison of MetaCyc (M) and KEGG (K) reaction attributes, for those attributes where one hundred or more objects have a value for that attribute

Attributes are sorted based on the MetaCyc frequency column. Attribute Physiologically-Relevant? describes whether a reaction occurs in vivo. Reaction-Direction specifies the directionality of the reaction. Orphan? is true when no nucleotide or amino-acid sequence has been determined for any enzyme catalyzing this reaction [39, 40]. Rxn-Locations specifies the cellular locations in which a reaction occurs (e.g., cytoplasm or mitochondrion). Spontaneous? specifies whether a reaction occurs spontaneously in living organisms and therefore requires no enzyme. KEGG reaction attribute data are derived from the KEGG REACTION dataset, and thus include glycan reactions.

ISSN: 1471-2105