Skip to main content

Table 2 Rank of entries from the ChEA gene-set library using the three scoring methods implemented in Enrichr given input of lists of up or down regulated genes indentified from studies that profiled gene expression after knockdown or knockout of the same transcription factors

From: Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

TF

Up/Down

PMID

Rank p-value

Rank z-score

Rank combined

Nanog

Up

16518401

1,4,5,16,

2,4,15,18,22,

1,5,12,16,18,

   

28,33,62,144

28,33,116

28,37,117

Nanog

Down

16518401

5,11,14,16,

1,3,4,20,41,

1,6,12,15,18,

   

39,58,78,92

54,61,64

56,70,73

Pou5f1

Up

16518401

3,11,12,18,

1,4,12,23,

1,8,14,15,

   

27,71,81

33,35,36

21,50,54

Pou5f1

Down

16518401

32,64,78,156,

1,65,92,121,

23,52,90,127,

   

176,181,204

160,165,188

171,176,192

Nanog

Up

16767105

3,7,12,18,38,

1,3,11,17,21,

3,5,9,12,25,

   

46,56,113

23,26,69

29,36,80

Nanog

Down

16767105

18,28,79,89,

4,17,21,33,44,

23,25,35,48,

   

92,102,160,164

83,139,157

60,86,142,186

Pou5f1

Up

16767105

1,9,18,23,31,

2,5,10,20,

1,2,16,20,

   

82,120,183

30,34,79

23,55,88

Pou5f1

Down

16767105

25,44,124,166,

47,49,60,131,

43,44,74,134,

   

167,180,216

139,169,200

147,153,177

Sox2

Up

16767105

2,10,35,59,61,

11,15,26,36,

3,9,26,44,

   

70,121

68,71,103

58,80,123

Sox2

Down

16767105

5,44,50,130,

10,72,85,106,

1,61,82,108,

   

139,149,176

110,140,151

116,166,177

Sox2

Up

17515932

2,14,15,41,50,

6,27,30,35,

2,7,24,39,44,

   

61,82

44,49,55

45,57

Sox2

Down

17515932

8,19,68,93,117,

6,29,73,95,

4,17,84,103,

   

164,216

124,146,210

132,151,168

klf4

Up

18264089

1,27,31,183

6,22,31,199

1,23,31,210

klf4

Down

18264089

61,71,163,200

78,85,190,222

78,79,209,219

Zfp281

Up

18757296

3,24

3,6

3,6

Zfp281

Down

18757296

60,159

63,138

64,147

chd1

Up

19587682

126

106

107

chd1

Down

19587682

231

214

125

Tbx3

Up

20139965

110

96

96

Tbx3

Down

20139965

93

70

76