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Figure 3 | BMC Bioinformatics

Figure 3

From: Compression-based distance (CBD): a simple, rapid, and accurate method for microbiota composition comparison

Figure 3

Comparison of 16S rDNA UniFrac and CBD using GIT microbiota of lean and obese twins[42]. CBD run on V6 and V2 16S rDNA sequences (average 24,786 ± 1,403 sequences per V6 sample and average 3,984 ± 232 sequences per V2 sample) demonstrated agreement with UniFrac analysis [42]. (a) Average unweighted UniFrac distance between family and non-family from Turnbaugh et al.[42] The graph was reproduced according to the value in the y-axis of Supplemental figure 1a from Turnbaugh et al.[42] (b) Average CBD between family and non-family (* P < 0.001; mean ± SEM). (c) Average unweighted UniFrac distance between Twin-Twin, Mother-Twin, and family-unrelated individuals, lean related and lean unrelated individuals, obese related and obese unrelated individuals from Turnbaugh et al.[42]. The graph was reproduced according to the value in the y-axis of Figure 1a from Turnbaugh et al.[42] (d) Average CBD between Twin-Twin, Mother-Twin, and family-unrelated individuals, lean related and lean unrelated individuals, obese related and obese unrelated individuals (* P < 0.05; mean ± SEM).

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