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Table 1 Comparison of cancergrid common data elements (CDEs) with CDEs from the association of pathology informatics data exchange specification (DES)

From: A metadata-aware application for remote scoring and exchange of tissue microarray images

Cancergrid CDE name

API DES XML tag name

Comments

Donor Tissue Block Identifier

core_histo-repository_donor-block

 

Tissue Microarray Recipient Block Identifier

block_identifier

 

Tissue Microarray Recipient Block Core Diameter

block_core_size

 

Tissue Microarray Recipient Block Core Spacing

block_core_spacing

 

Tissue Microarray Recipient Block Core Position Used

 

Used to indicate a gap in the TMA Recipient Block where a core has not been inserted.

Tissue Microarray Recipient Block Slice Number

 

Useful for querying whether a core image is from a slice adjacent to another core image.

Tissue Microarray Recipient Block x coordinate

 

block_array-hash describes the x,y location for each core in the block array, associating an identifier with each core location.

Tissue Microarray Recipient Block y coordinate

 

Tissue Microarray Slide Identifier

slide_identifier

 

Tissue Microarray Core Element Identifier

 

core_array_id serves the same function, to uniquely identify a core within a TMA Recipient Block

Allred Intensity Score

 

core_results_tissue-intensity is a more general numerical value to define the relative intensity of staining

Allred Proportion Score

 

Represents a specific staining system.

Allred Score for ER status

  

Percentage tissue staining

core_results_percent-tissue-staining

 

HER2 status by immunohistochemistry

 

Represents a specific staining system.

Binary biomarker staining result

 

A simple scoring system with a binary value to indicate whether the tissue is positively or negatively stained for a particular marker.