Figure 1

The processing result of the region chr21:37.0∼37.1 Mbs (zoom in of the region between the vertical magenta lines in Figure 6). The black dots are the read depths; the blue line is the smoothed signal x _i ; the red line is the corrected smoothed signal ${\tilde{x}}_i$; the horizontal green lines are the lower and upper cutoff values estimated from the histogram; and the thick red lines highlight the detected CNVs. Note that a small CNV at region 37.04 with length 1.1 kbp is detected.