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Table 5 Number of differentially bound regions at 5% FDR when making an assumption of the same number of binding sites for the two proteins ( p 1  = p 2 ), compared to the case when this assumption is not made ( p 1  ≠ p 2 ); the last column reports the difference in the BIC values of the two models (a positive difference means a better fit for the model that assumes p 1  = p 2 )

From: Accounting for immunoprecipitation efficiencies in the statistical analysis of ChIP-seq data

Conditions

# Regions bound only by CBP

# Regions bound only by p300

BIC difference

 

p1 ≠ p2

p1 = p2

p1 ≠ p2

p1 = p2

BIC p 1 p 2 - BIC p 1 = p 2

T0

9

11

2726

1277

16172.34

Wang

3069

2630

142

142

3267.04