Table 1 A comparison of the most significant iPAC and NMC p-values from the 8 proteins that were picked up by both algorithms
From: Utilizing protein structure to identify non-random somatic mutations
iPAC | NMC | |||
|---|---|---|---|---|
Protein | P-value | P* | P-value | P* |
KRAS | 6.17 E-185 | 6.35 E-181 | 4.39 E-233 | 4.52 E-229 |
TP53 | 5.23 E-128 | 6.11 E-123 | 4.37 E-086 | 5.30 E-81 |
BRAF | 3.73 E-130 | 1.01 E-126 | 3.84 E-130 | 1.04 E-126 |
PIK3CA | 8.20 E-084 | 3.58 E-80 | 8.20 E-084 | 3.58 E-80 |
NRAS | 5.38 E-026 | 6.46 E-24 | 8.26 E-029 | 9.91 E-27 |
HRAS | 1.23 E-010 | 5.54 E-09 | 5.61 E-010 | 8.42 E-09 |
AKT1 | 1.18 E-005 | 7.08 E-05 | 2.47 E-005 | 7.41 E-05 |
IDE | 2.20 E-005 | 6.60 E-05 | 1.56 E-003 | 4.67 E-03 |