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Table 10 The 10 top-ranked informative genes found by the three sparse logistic regression methods from the DLBCL dataset

From: Sparse logistic regression with a L1/2 penalty for gene selection in cancer classification

Rank

Gene description

 

L1/2

LEN

L1

1

CCL21 chemokine (C-C motif) ligand 21 *

MTH1 metallothionein 1H *

MTH1 metallothionein 1H *

2

HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 *

MT2A metallothionein 2A *

MT2A metallothionein 2A *

3

MT2A metallothionein 2A *

SFTPA1 surfacant protein A1 *

CCL21 chemokine (C-C motif) ligand 2 *

4

THRSP thyroid hormone responsive *

TCL1A T-cell leukemia/lymphoma 1A *

SFTPA1 surfacant protein A1 *

5

lgj immunoglobulin joining chain *

ZFP36L2 ZFP36 ring finger protein-like 2 *

POLD2 polymerase (DNA directed), delta 2, accessory subunit *

6

TCL1A T-cell leukemia/lymphoma 1A *

FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) *

lgj immunoglobulin joining chain *

7

GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) *

lgj immunoglobulin joining chain *

MELK maternal embryonic leucine zipper kinase *

8

Plod procollagen lysyl hydroxylase *

TRB2 Homeodomain-like/winged-helix DNA-binding family protein *

CKS2 CDC28 protein kinase regulatory subunit 2 *

9

STXBP2 syntaxin binding protein 2 *

MELK maternal embryonic leucine zipper kinase *

EIF2A eukaryotic translation initiation factor 2A, 65kDa *

10

SFTPA1 surfacant protein A1 *

CCL21 chemokine (C-C motif) ligand 2 *

AQP4 aquaporin 4 *

  1. The genes with star(*) are the most frequently selected genes to construct the classifiers according to the last column of Table 6, and the common genes obtained by L1/2 , LEN , L1 classifiers are emphasized with bold.