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Table 10 The 10 top-ranked informative genes found by the three sparse logistic regression methods from the DLBCL dataset

From: Sparse logistic regression with a L1/2 penalty for gene selection in cancer classification

Rank Gene description
  L1/2 LEN L1
1 CCL21 chemokine (C-C motif) ligand 21 * MTH1 metallothionein 1H * MTH1 metallothionein 1H *
2 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 * MT2A metallothionein 2A * MT2A metallothionein 2A *
3 MT2A metallothionein 2A * SFTPA1 surfacant protein A1 * CCL21 chemokine (C-C motif) ligand 2 *
4 THRSP thyroid hormone responsive * TCL1A T-cell leukemia/lymphoma 1A * SFTPA1 surfacant protein A1 *
5 lgj immunoglobulin joining chain * ZFP36L2 ZFP36 ring finger protein-like 2 * POLD2 polymerase (DNA directed), delta 2, accessory subunit *
6 TCL1A T-cell leukemia/lymphoma 1A * FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) * lgj immunoglobulin joining chain *
7 GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) * lgj immunoglobulin joining chain * MELK maternal embryonic leucine zipper kinase *
8 Plod procollagen lysyl hydroxylase * TRB2 Homeodomain-like/winged-helix DNA-binding family protein * CKS2 CDC28 protein kinase regulatory subunit 2 *
9 STXBP2 syntaxin binding protein 2 * MELK maternal embryonic leucine zipper kinase * EIF2A eukaryotic translation initiation factor 2A, 65kDa *
10 SFTPA1 surfacant protein A1 * CCL21 chemokine (C-C motif) ligand 2 * AQP4 aquaporin 4 *
  1. The genes with star(*) are the most frequently selected genes to construct the classifiers according to the last column of Table 6, and the common genes obtained by L1/2 , LEN , L1 classifiers are emphasized with bold.