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Table 8 The 10 top-ranked informative genes found by the three sparse logistic regression methods from the Prostate dataset

From: Sparse logistic regression with a L1/2 penalty for gene selection in cancer classification

Rank

Gene description

 

L1/2

LEN

L1

1

SLC43A3 solute carrier family 43, member 3 *

AMOTL2 angiomotin like 2 *

USP4 ubiquitin specific peptidase 4 (proto-oncogene) *

2

CD22 CD22 molecule *

USP4 ubiquitin specific peptidase 4 (proto-oncogene) *

CD22 CD22 molecule *

3

KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 *

EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 *

EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 *

4

ZNF787 zinc finger protein 787 *

PRAF2 PRA1 domain family, member 2 *

Gene symbol:AA683055, probe set: 34711_at *

5

GMPR guanosine monophosphate reductase *

CACYBP calcyclin binding protein *

AMOTL2 angiomotin like 2 *

6

AMOTL2 angiomotin like 2

Gene symbol:AA683055, probe set: 34711_at *

VSNL1 visinin-like 1 *

7

EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2

VSNL1 visinin-like 1 *

FLNC filamin C, gamma *

8

USP2 ubiquitin specific peptidase 2

SLC43A3 solute carrier family 43, member 3 *

PRAF2 PRA1 domain family, member 2 *

9

USP4 ubiquitin specific peptidase 4 (proto-oncogene)

CD22 CD22 molecule *

CACYBP calcyclin binding protein *

10

ACTN4 actinin, alpha 4

TMCO1 transmembrane and coiled-coil domains 1 *

SLC43A3 solute carrier family 43, member 3 *

  1. The genes with star(*) are the most frequently selected genes to construct the classifiers according to the last column of Table 6, and the common genes obtained by L1/2 , LEN , L1 classifiers are emphasized with bold.