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Table 9 The 10 top-ranked informative genes found by the three sparse logistic regression methods from the colon dataset

From: Sparse logistic regression with a L1/2 penalty for gene selection in cancer classification

Rank Gene description
  L1/2 LEN L1
1 GUCA2B guanylate cyclase activator 2B (uroguanylin) * GUCA2B guanylate cyclase activator 2B (uroguanylin) * GUCA2B guanylate cyclase activator 2B (uroguanylin) *
2 MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle * MYH9 myosin, heavy chain 9, non-muscle * ATPsyn-Cf6 ATP synthase-coupling factor 6, mitochondrial *
3 DES desmin * DES desmin * MYH9 myosin, heavy chain 9, non-muscle *
4 CHRND cholinergic receptor, nicotinic, delta polypeptide * MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle * GSN gelsolin *
5 PECAM1 platelet/endothelial cell adhesion molecule-1 * GSN gelsolin * MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle *
6 ATPsyn-Cf6 ATP synthase-coupling factor 6, mitochondrial COL11A2 collagen, type XI, alpha 2 * COL11A2 collagen, type XI, alpha 2 *
7 ATF7 activating transcription factor 7 ATPsyn-Cf6 ATP synthase-coupling factor 6, mitochondrial * MXI1 MAX interactor 1, dimerization protein *
8 PROBABLE NUCLEAR ANTIGEN (Pseudorabies virus)[accession number:T86444] ssb single-strand binding protein * UQCRC1 ubiquinol-cytochrome c reductase core protein I *
9 MYH9 myosin, heavy chain 9, non-muscle Sept2 septin 2 * DES desmin *
10 MYH10 myosin, heavy chain 10, non-muscle MXI1 MAX interactor 1, dimerization protein * ZEB1 zinc finger E-box binding homeobox 1*
  1. The genes with star(*) are the most frequently selected genes to construct the classifiers according to the last column of Table 6, and the common genes obtained by L1/2 , LEN , L1 classifiers are emphasized with bold.