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Table 9 The 10 top-ranked informative genes found by the three sparse logistic regression methods from the colon dataset

From: Sparse logistic regression with a L1/2 penalty for gene selection in cancer classification

Rank

Gene description

 

L1/2

LEN

L1

1

GUCA2B guanylate cyclase activator 2B (uroguanylin) *

GUCA2B guanylate cyclase activator 2B (uroguanylin) *

GUCA2B guanylate cyclase activator 2B (uroguanylin) *

2

MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle *

MYH9 myosin, heavy chain 9, non-muscle *

ATPsyn-Cf6 ATP synthase-coupling factor 6, mitochondrial *

3

DES desmin *

DES desmin *

MYH9 myosin, heavy chain 9, non-muscle *

4

CHRND cholinergic receptor, nicotinic, delta polypeptide *

MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle *

GSN gelsolin *

5

PECAM1 platelet/endothelial cell adhesion molecule-1 *

GSN gelsolin *

MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle *

6

ATPsyn-Cf6 ATP synthase-coupling factor 6, mitochondrial

COL11A2 collagen, type XI, alpha 2 *

COL11A2 collagen, type XI, alpha 2 *

7

ATF7 activating transcription factor 7

ATPsyn-Cf6 ATP synthase-coupling factor 6, mitochondrial *

MXI1 MAX interactor 1, dimerization protein *

8

PROBABLE NUCLEAR ANTIGEN (Pseudorabies virus)[accession number:T86444]

ssb single-strand binding protein *

UQCRC1 ubiquinol-cytochrome c reductase core protein I *

9

MYH9 myosin, heavy chain 9, non-muscle

Sept2 septin 2 *

DES desmin *

10

MYH10 myosin, heavy chain 10, non-muscle

MXI1 MAX interactor 1, dimerization protein *

ZEB1 zinc finger E-box binding homeobox 1*

  1. The genes with star(*) are the most frequently selected genes to construct the classifiers according to the last column of Table 6, and the common genes obtained by L1/2 , LEN , L1 classifiers are emphasized with bold.