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Table 3 Comparisons of features between SeqSIMLA and SIMRARE

From: SeqSIMLA: a sequence and phenotype simulation tool for complex disease studies

Feature

SeqSIMLA

SimRare

Language

C++/Java

Python/C++

Sequence simulator

GENOME (default) or a sequence pool generated by a simulator

srv in SimuPOP

Simulated region

Multiple genes on multiple chromosomes

A gene or multiple independent genes

Simulated data type

Families/unrelated cases and controls

Unrelated cases and controls

Recombination rate

Variable/Fixed

Fixed

Number of disease/trait models

3

6

User interface

Command line

Graphical