Skip to main content

Table 1 Description of response and explanatory variables subjected to decision tree analyses

From: Infection status outcome, machine learning method and virus type interact to affect the optimised prediction of hepatitis virus immunoassay results from routine pathology laboratory assays in unbalanced data

Variable abbreviation

Description & definition

Measurement units

 

Response variable

 

HBSA

Hepatitis B Surface Antigen (marker of HBV infection)

Positive (1) or

HepC

Patient antibody to HCV, indicating contact with virus (Both HBSA and HepC detected by immunoassay)

Negative (0)

 

Explanatory variable

 

Age

Patient (case) Age

Years

Sex

Gender: 1 = F, 2 = M

M or F

ALT

Alanine aminotransferase (An intracellular enzyme released in after liver & other tissue cell damage)

U/L

GGT

Gamma-glutamyltranspeptidase (An intracellular enzyme also relevant to liver damage)

U/L

Hb

Haemoglobin

g/L

Hct

Haematocrit (formerly known as “packed cell volume”)

%

Mch

Mean corpuscular haemoglobin

pg/RBC

MCHC

Mean corpuscular haemoglobin concentration

g/L

MCV

Mean corpuscular volume

fL

Plt

Platelets (blood clotting)

x 109/L

WCC

White cell count

x 109/L

RCC

Red cell count

x 1012/L

RDW

Red cell distribution width

%

Neut

Neutrophil. White blood cell, elevated by bacterial infection and early viral infection

x 109/L

Lymph

Lymphocyte. White blood cell, elevated by viral infection and some cancers

x 109/L

Mono

Monocyte. White blood cell, elevated by infection, inflammation, some cancers.

x 109/L

Eos

Eosinophil. White blood cell, elevated by allergy and parasite infection

x 109/L

Bas

Basophils. White blood cell, elevated in hypersensitivity reactions.

x 109/L

  1. U/L Units per litre, g/L grams/Litre, pg picograms, fL femtolitres.