Machine learning methods can replace 3D profile method in classification of amyloidogenic hexapeptides

BMC Bioinformatics

Table 3 ZipperDB versus other methods

Method	Overlap	Positive	Negative
1. FoldAmyloid Contacts	0.77	0.36	0.86
2. FoldAmyloid Bone-Bone Donors	0.79	0.39	0.88
3. FoldAmyloid Bone-Bone Acceptors	0.78	0.39	0.86
4. FoldAmyloid Contacts+Donors	0.78	0.38	0.87
5. FoldAmyloid *Contacts+Donors+Acceptors*	0.77	0.43	0.84
6. Waltz Best Performance	0.81	0.11	0.97
7. Waltz High Sensitivity	0.80	0.30	0.91
CONSENSUS 3D profile + (5) + (7)	0.69	0.21	0.65

ISSN: 1471-2105