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Table 2 Key words used and selection of Pfam domains for protein vaccine candidate prediction

From: Jenner-predict server: prediction of protein vaccine candidates (PVCs) in bacteria based on host-pathogen interactions

Sr. No.

Key word used for PFam domain search

No of domain hits

No of selected domains*

Reference

1.

Adhesin

166

96

19

2.

Choline binding protein

29

12

20

3.

Bacterial extracellular solute-binding protein

36

8

21

4.

Porin

66

46

22

5.

Invasin

30

25

23

6.

Fibronectin-binding protein

50

25

24

7.

Transferrin-binding protein

24

6

25

8.

Virulence

402

145

26

9.

Penicillin-binding Protein

14

8

27

10.

Flagellin

22

12

28

11.

Colonization

23

14

29

12.

Host-pathogen interaction

9

4

30

13.

Toxin

542

110

31

  1. *Only those families/domains were included which are involved in host-pathogen interactions and/or pathogenesis.