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Figure 1 | BMC Bioinformatics

Figure 1

From: RCytoscape: tools for exploratory network analysis

Figure 1

A static display of (a) tumor TCGA.02.0014 and (b) TCGA.0.0835. mRNA differential expression, copy number and mutation data mapped onto the same composite reference PDGFRA-neighborhood subnetwork (KEGG ‘Pathways in Cancer’, ‘Glioma’, ‘Cell Cycle’). (c) Key: Node color indicates differential expression (log-fold-change with respect to normal brain tissue). (d) Edges indicate molecular relationships as indicated. (e) Node shape indicates functional gene type; node border color and width indicates genomic copy number. Node size indicates possible tumorigenic importance, a function of mRNA expression, copy number and non-synonymous mutation. Non-aberrant genes and relationships are dimmed out.

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