Empirical assessment of competitive hybridization and noise in ultra high density canine tiling arrays

BMC Bioinformatics

Table 3 REML output for the distance dataset

Fixed term	Fstatistic	P-value	Effect	Standard error
Probe GC	976.27	<0.001	0.068	0.002
log_e Off-targets	14.49	<0.001	0.421	0.111
Free energy	100.23	<0.001	0.165	0.016
PolyA	5.05	0.030	0.036	0.016
PolyC	9.20	0.005	0.167	0.056
PolyG	13.16	0.012	0.100	0.027
PolyT	13.94	<0.001	0.058	0.016
Offset	31.25	<0.001		0.037^a
6 bp			0
26 bp			0.210
log_e Background	15.28	<0.001	0.124	0.032
log_e Segment length	2.11	0.146	-0.019	0.013
log_e Distance	3.96	0.047	0.024	0.012

^a Standard error of the difference between the effect of 6 bp or 26 bp offset.
This probe set included the first and last tiled probe within each tiled segment, after filtering. The predicted effects of each variable and factor level on hybridization intensity (log_e scale) are shown and the associated standard error of predicted effects.

ISSN: 1471-2105