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Table 3 Composite element in prostate specific promoters

From: MatrixCatch - a novel tool for the recognition of composite regulatory elements in promoters

Name1 Gene Position2 Strand S 1 3 S 2 3 CS p-value Sequence
Original composite element sequence         ATGAGGCAAT           cggcact  GTTGCCACAT
uc002uum.1 MOB4 −346 + 0.972 0.976 0.012 3.801e-06 AGTTTGCGAAAAT              gctgtg     GTTTCTTAAGAGA
uc003jwu.1 OCLN −213 + 0.973 0.949 0.202 9.234e-05  AGATTCAGAAACA    gcgccaatg       TTTACACACGACT
uc003qcg.1 EPB41L2 −100 + 0.988 0.981 0.099 1.418e-06  AGATTTTGAAATG          ctac          TTTTCACAAAATA
uc001iia.1 NET1 −369 + 0.991 0.765 0.207 1.091e-05   ACCTTTGGTAATT      ggaaat          ATATCTCATATTG
uc002eby.1 ZNF843 −352 + 0.963 0.929 0.123 1.895e-04    AGCCTAGGCAAAA        gagcacg     ATTCCGTCTCAAG
uc004dpe.1 SHROOM4 +3 + 0.961 0.915 0.140 3.402e-04    TGCTATTGTAAAT         ggaactg   TTTTCTTTCTTTC
Sequence complementary to the original composite element sequence            ATGTGGCAAC       agtgccg   ATTGCCTCAT
uc003edg.1 C3orf15 −317 - 0.946 0.959 0.110 1.347e-04    TGGCTGAGAAAAT     caatgac      ATTGCTTATGAAA
uc003fsb.1 TP63 −345 - 0.924 0.972 0.228 2.397e-04   ACAAAGAGTAAAA  agaaaag       TTTTCATAAAGGA
uc003gno.1 C1QTNF7 −27 - 0.947 0.997 0.234 4.040e-06    AAACTGAGAAAGA     taa               CTTTCTGAAATGC
uc003xye.1 SULF1 −333 - 0.728 0.987 0.304 1.456e-04    AAAGAAAGGTAGG      ca               GTTGCAAAACTTC
uc002tah.1 AFF3 −149 - 0.922 0.993 0.046 4.600e-06    TCAGAAGGAAAAA      agtttag      ATTTCAAAATGTA
uc003sli.1 MAD1L1 +2 - 0.761 0.981 0.276 1.790e-04     TGTCTAGGGGAGA   taaaat          CTTGCCTAAGCAA
uc003zwl.1 KIAA1539 −310 - 0.760 0.959 0.300 8.385e-04      CTCCGTAGTCACC   agatttt          ATTTCACAAGGTG
uc001lwy.1 SLC22A18 −113 - 0.939 0.965 0.167 1.691e-04     CGCTCCCGGAACT  tccat           TTTACATATGAGG
uc001wpn.1 SDR39U1 −12 - 0.767 0.993 0.313 3.045e-05     TTAGTGAGACAAT      ggcg      ATTGCAAAGCGCG
uc004env.1 COL4A6 −44 - 0.752 0.981 0.285 2.156e-04     TGAGATGGACATT        ttattttt      ATTGCCTAAACTG
  1. Composite regulatory element C/EBP / C/EBP recognized in promoters of genes active in prostate tissue. Nucleotides with significant conservation shown in bold (within binding motifs) and italics (intermediate sequence).
  2. 1 Names according to (Jacox et al., [12]).
  3. 2 Beginning of the element relative to TSS.
  4. 3S 1,2 - PWM scores for the first and second C/EBP motif, CS - composite score.