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Figure 1 | BMC Bioinformatics

Figure 1

From: Hierarchical Bayesian modelling of gene expression time series across irregularly sampled replicates and clusters

Figure 1

An illustration of a simple hierarchical GP. Top: the prior over the underlying function g n (t), with the mean μ(t)=0 shown as a heavy solid line, and the shaded area representing the variance (amplitude) of the function, controlled by the hyper-parameter α g . A single sample from the prior is shown as a narrow line, and the length-scale of the function, inversely controlled by the hyper-parameter γ g , is marked. Middle: three functions, representing three replicates are shown, along with samples conditioned on the sample shown in g n (t). The three replicates follow the trend of g n (t), but deviate independently by a small amount (variance α f ) with a short length-scale, marked in the third replicate. Bottom: the covariance matrix used to generate the samples Σ n . Note the block-wise relationship to the replicates.

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