Table 2 A selection of regions of local enrichment that could not be found using standard TFBS over-representation analysis
Tissues or cell types (cluster index) | Transcription factor | Region of enrichment: | PORI | References |
|---|---|---|---|---|
| Â | Â | x1to x2( h/ 2) | Â | Â |
B cells, T cells (2) | ETS domain TFs, including SPI1 or PU.1 | -10 to 0 (10) | 0.15 | |
B cells, T cells (2) | HIF1 | 55 to 200 (200) | 0.11 | [46] |
testis (10) | RFX1 | -91 to 129 (200) | 0.012 | |
testis (10) | CREB-binding TFs, including ATF family | -148 to 31 (100) | 0.035 | |
liver (16) | Cux1 (CR3 + HD) | -103 to -90 (10) | 0.037 | [51] |
small and large intestine (19) | HNF1 | -93 to -37 (20) | 0.012 | [52] |
small and large intestine (19) | RXR, RAR, and VDR | -52 to -43 (10) | 0.065 | |
testis (22) | MYB family TFs | -72 to 95 (100) | 0.025 | |
testis (22) | heat shock factors | -58 to 217 (200) | 0.032 | [57] |
skeletal muscle (42) | THR alpha and beta | -30 to -15 (50) | 0.025 |