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Table 1 Estimated fold change of 10 genes from one sample of simulated dataset2 using NPEBSeq, DESeq and edgeR

From: NPEBseq: nonparametric empirical bayesian-based procedure for differential expression analysis of RNA-seq data

gene_ID 9995 9996 9511 9032 9045 9030 9082 3 1
Poisson mean under condition A 0.7741 1.4868 11.5416 424.1334 5.2419 5.2419 112.1307 0.7741 86.6691
Poisson mean under condition B 3.0318 5.8233 45.2038 103.8228 1.2832 1.2832 27.4483 0.758 84.8622
TRUE fold change 4 4 4 4 4 4 4 1 1
observed #reads under condition A 0 0 2 365 34 13 89 0 80
observed #reads under condition B 4 2 37 111 0 1 83 4 72
estimated fc by NPEBSeq 2.5813 1.8077 13.2633 3.3515 18.9702 5.8962 1.1168 2.5813 1.0156
estimated fc by DESeq inf inf 18.6932 3.2543 inf 12.8656 1.0612 inf 1.0996
estimated fc by edgeR 60.4244 24.121 58.9655 5.3961 1192.127 29.3642 1.0736 60.4244 1.1299