Figure 6
From: Ontology based molecular signatures for immune cell types via gene expression analysis
Candidate genes involved in the unique functions of Germinal Center B cells. A) Gene Ontology term enrichment of germinal center B cells (GC B cell) reveals genes involved in cell cycling and in the repair of DNA. B) DNA repair is often associated with cellular proliferation, so a new set of pairwise comparisons was generated against other proliferating lymphocytes using the methods described. Marginal zone B cells were included to eliminate genes found among B cells. C ) Table of Top 10 genes overexpressed in GC B cells compared to activated lymphocytes and MZ B cells. * Probe maps to two different IgKappa variable segments.