TY - JOUR AU - Bérard, Caroline AU - Seifert, Michael AU - Mary-Huard, Tristan AU - Martin-Magniette, Marie-Laure PY - 2013 DA - 2013/09/09 TI - MultiChIPmixHMM: an R package for ChIP-chip data analysis modeling spatial dependencies and multiple replicates JO - BMC Bioinformatics SP - 271 VL - 14 IS - 1 AB - Chromatin immunoprecipitation coupled with hybridization to a tiling array (ChIP-chip) is a cost-effective and routinely used method to identify protein-DNA interactions or chromatin/histone modifications. The robust identification of ChIP-enriched regions is frequently complicated by noisy measurements. This identification can be improved by accounting for dependencies between adjacent probes on chromosomes and by modeling of biological replicates. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-14-271 DO - 10.1186/1471-2105-14-271 ID - Bérard2013 ER -