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Table 1 Cross-validated results showing the performance of the three search strategies in positioning targets to within the published error margin of OPM

From: Membrane protein orientation and refinement using a knowledge-based statistical potential

 

Within OPM error

Outside OPM error

All targets

Search type

Type

Within OPM error

Mean tilt

Max tilt

Mean tilt

Max tilt

Mean tilt

Max tilt

GA

Alpha

86.9%

0.56

2.98

3.58

7.61

1.07

2.12 

Direct

Alpha

80.3%

0.77

4.83

6.94

28.44

1.98

2.66 

Grid

Alpha

79.2%

0.74

3.74

5.04

14.68

1.63

1.67 

GA

Beta

80.6%

1.03

3.62

9.25

20.02

3.77

3.82 

Direct

Beta

83.3%

1.76

6.90

13.71

29.97

3.75

3.03 

Grid

Beta

77.7%

2.35

10.03

14.12

37.64

4.97

2.74 

  1. Type indicates alpha-helical or beta-barrel. Tilt angles are the deltas compared to OPM and are measured in degrees. Mean z-shift is the mean z-coordinate delta compared to OPM calculated using all transmembrane segment boundary residues, measured in angstroms.