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Table 4 Parameter settings of simulated data for Case 1

From: Large-scale multiple testing in genome-wide association studies via region-specific hidden Markov models

Chromosome Region Transition matrix z-value distribution z-value distribution
(c) (r)   (Null) (Non-null)
1 1 0.98 0.02 0.03 0.97 N(0,1) N( μ 11 ( 1 ) ,1)
  2 0.98 0.02 0.03 + υ 1 0.97 - υ 1 N(0,1) N( μ 21 ( 1 ) = μ 11 ( 1 ) +1.5,1)
2 1 0.98 0.02 0.05 0.95 N(0,1) N( μ 11 ( 2 ) = μ 11 ( 1 ) +0.5,1)
  2 0.98 0.02 0.05 + υ 1 0.95 - υ 1 N(0,1) N( μ 21 ( 2 ) = μ 11 ( 2 ) +2.0,1)